Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention.
C-type lectins are a family of proteins with carbohydrate-binding activity.Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.We previously identified a C-type lectin in Aedes aegypti, designated as mosquito galactose specific C-type lectin-1 (mosGCTL-1), facilitating th